The very concept that is based on the book of Japan Kazuo Ishiguro is really an absurd vision of the future and might not be considered fully original by itself - clones are created to later donate their organs - but by letting it take place in our time "Never Let Me Go" differs from the others and makes it easier to relate to. We witness a parallel world where something bad is considered normal, and the less weight the story adds to the world's moral issues, the deeper the hopelessness creeps inside the audience.
I felt however that a number of occasions were missed and many questions left unanswered when the end credits began to roll. Admittedly, the filmmakers chose to focus on the romantic aspect, but it's a shame when you have so much more good material to work with. Instead Never Let Me Go answers to what the outcome would be if Jane Austen wrote a sci-fi, a question very few probably asked themselves.